#RHEUMATOID ARTHRITIS DIAGNOSIS CRITERIA 2020 SKIN#

Their appearance is also characteristic of the affected joints, nodules under the skin can be probed in a painless form of dense pellets.

Many of these symptoms are caused by the formation of the so-called rheumatoid nodules - small lumps of connective tissue in the organs. In addition to joint symptoms in Rheumatoid arthritis may cause other injuries: thinning and brittle nails, muscle weakness of the skeleton, the development of gastritis gipatsidnogo, pleurisy, lung tissue damage. Relapsing disease course, each subsequent re-aggravation of acute painful at first accompanied by swelling of the joints, and then the progression of their deformity. Thus, in RA suggests deformation of individual fingers to type 'swan neck' or the whole brush-type 'fin walrus.' In the deformed joints hindered movement, impaired function of the elasticity of the brush and brake, causing the patient becomes virtually disabled and unable to maintain itself. Characterized by specific changes in the configuration of fingers due to the persistent flexion or hyperextension of the joints. In the future, an acute inflammatory edema subsides, but the form of deformation of the joints, especially the small joints of hands and feet. Affected joints are enlarged, reddish, with a warm skin over their surface, sharply painful when touched before them. The more active the disease, the greater the period of morning stiffness is observed. Pain and stiffness are more intense in the morning and gradually diminish in the evening.

#RHEUMATOID ARTHRITIS DIAGNOSIS CRITERIA 2020 FULL#

The pain is accompanied by a feeling of stiffness in the joints, loss of full range of motion in them. In the future, there are pains in the joints.Д¬haracteristically, the first affects the small joints of hands and feet, symmetrical lesion. The first symptoms of RA and non-specific like a banal cold: malaise, fatigue, weight loss, periodic aching muscle pain, sweating and a slight rise in temperature. Note also link the disease with the spring-autumn season and periods of physiological adjustment of the organism (adolescence, the period after childbirth in women, menopause). Often triggered by the beginning of the transferred acute infection, hypothermia, or a stressful situation. The disease onset is most often subacute, predominantly affects women in middle age. The cause of the disease is not clear, but it is assumed that it is based on changes in the immune response of the organism on its own connective tissue, this change may trigger a number of viruses, antibodies are sometimes found in the blood of patients with RA. Defeat it occurs predominantly in the joints of the hands and feet.

Such findings suggest that morning symptoms in RA remain an important marker of active disease that should continue to be monitored.Rheumatoid arthritis - a chronic disease that affects the connective tissue of the body. However, such measures may not capture all disease activity, and one in six patients in remission or with low disease activity still experiences prolonged morning stiffness. Measures that are widely used to monitor disease control also omit morning stiffness. Established diagnostic criteria for RA include morning stiffness, although it is not part of the more recent classification criteria developed to guide early treatment decisions. In RA, the increase in nocturnal anti-inflammatory cortisol secretion is insufficient to suppress ongoing inflammation, resulting in the morning symptoms characteristic of RA. These symptoms closely follow the circadian rhythm of the pro-inflammatory cytokine, interleukin (IL)-6. In rheumatoid arthritis (RA), clinical symptoms of joint stiffness, pain, and functional disability are commonly most severe in the early morning. Pathological manifestations of this system may also follow circadian rhythms. Many human biological processes are regulated by circadian rhythms, which follow 24-h cycles and involve the neuroendocrine and immune systems.

Rheumatoid arthritis diagnosis criteria 2020